Grimsby are expected to be without James McKeown for the clash with Accrington.
The goalkeeper limped off with a groin problem just 33 minutes into the Boxing Day draw with Mansfield and is awaiting the results of scans.
Ben Killip made his English Football League debut and the 22-year-old is set to continue in McKeown's absence.
Scott Vernon and JJ Hooper both came off the bench against the Stags and are pushing for a start.
Accrington skipper Seamus Conneely is hoping to recover from a recurrence of a groin injury in time to feature.
Right-back Conneely was an unused substitute in the Boxing Day defeat at Carlisle, but could return as John Coleman's side bid to avoid a fifth straight league defeat.
Defender Jordan Thorniley remains doubtful after missing out at Carlisle due to a similar problem, while Erico Sousa is pushing for a recall after his recent leg injury.
Accrington have lost their last five games in all competitions and are chasing their first league win on the road since October.